When we are young our hair is strong and vital and grows rapidly to replace itself through the normal hair fall cycle. It is also strongly pigmented and thick, bursting with the health of the young. The aging process affects hair growth just as it affects other parts of the body and the hair strands grow more thinly and becomes brittle. The growth rate also slows and the pigmentation begins to fade which presents itself as the greying process.
From this point people begin to look for ways to combat the aging process with various topical treatments such as conditioners, anti-aging shampoos and hair regrowth serums.
Results vary depending on the situation that has caused the loss of hair with some people experiencing only minimal results over long periods of time. A vast majority of commercial products that are being marketed as eyebrow growth or hair enhancement products that are showing a certain level of promise are the ones that cntain copper peptides.
What Are Copper Peptides?
The effectiveness of copper peptides in hair growth has been studied for a number of years and it was found in trials that it stimulated the growth of dermal papilla cells (DPCs). Human hair follicle organ culture resulted in the elongation of hair by more than 150% compared to the non-treated areas.
Skin Renewal Copper Peptides (SRCPs) are the copper peptides that renew the skin and this renewal process is linked very closely to the process of hair regrowth because of the effects on hair follicles. In return, the fact that copper peptides enhance the size and growth of hair follicles means that the blood vessels carry more blood to the area and the skin growth is enhanced.
The human copper peptide complex is known as glycyl-l-histidyl-l-lysine:copper (II) or GHK-Cu for short. This is a naturally occurring chemical in the body and can be found in blood plasma, urine and saliva. The studies that have been performed have shown that GHK-Cu only has to be in contact with the skin for a short amount of time for positive growth is noticed.
Not only does it enhance skin repair but it also has anti-inflammatory capabilities as well.
One of the foremost authorities in the use of copper peptides has been Dr Loren Pickart who established a company called ProCyte. Through this company there has been a great deal of development of various research projects that have resulted in products created for commercial use.
Do Copper Peptides Help To Regrow Eyebrows?
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The most pertinent question that most people reading this will want answered is just how effective are copper peptides in promoting hair growth in the eyebrow region. The simple answer is that they are very effective at improving the health of the hair follicles and this, in turn, improves the growing conditions.
As long as the hair follicles are live and in working order to start with you can expect that using a cream or serum containing copper peptides will eventually result in hair growth in the area. The extent to which the hair follicles were originally damaged will determine the length of time it will take before improvements are noticed.
As with all types of restorative methods, the hair must go through its growth cycle when regrowing new hair that may have been lost through trauma or other means. This could mean that it will be necessary to be patient when waiting for the first signs of new growth.
How Copper Peptides Improve General Hair Vitality
SRCPs can be seen to improve the health of hair and its growth in a number of different ways. We can list a few of them below to get an idea of just how effective it is.
Enlarge Follicles. It has been noted that when GHK-cus were used for wound healing the size of hair follicles and their sebaceous glands were markedly larger.
Longer Anagen Phase. The anagen phase refers to the growth phase of a hair follicle. By increasing the anagen phase the life cycle of the hair is increased and this slows down the hair loss process.
Protective Anti-Inflammatory Properties. Without going into too much scientific analysis it has been demonstrated that peptides are effective as a therapeutic benefit for treating inflammatory disease. This inflammation research piece describes some of the work done and results achieved in using peptides as an anti-inflammatory.
GHK-Cu works as a circulating non-steroidal anti-inflammatory by blocking ferritin channels and stopping the release if oxidizing iron ions. When soft tissue damage taken place ferric ion is released from ferritin and catalyzes damaging tissue oxidations. It also blocks the oxidation of low density lipoproteins by loosely bound copper.
The anti-inflammatory actions of copper peptides function to shut down the initial phase of wound sterilization and scar formation.
An additional benefit of the use of GHK is the anti-oxidant actions that come from using it. There are examples of studies in which GHK-Cu was tested for tissue protective properties and wound healing properties. It has also been found to markedly inhibit intestinal mucosal tissue from lipid peroxidation by oxygen-derived free radicals.
Repair Damaged Scalp. The skin restorative properties of copper peptides have been well documented and when it is applied to the skin of the scalp those properties will apply.
Reduce Graying. When products containing copper peptides have been used by some people they have reported that there was a reversal of the greying process. According to Dr Loren Pickart this is because “the formation of hair pigment is controlled by a copper enzyme called tyrosinase”.
How Safe Are Copper Peptides?
There have been many tests performed to ascertain the safety factor of applying copper peptides to the skin. There has never been any indication of toxicity problems following the application.
Extremely small amounts penetrate the skin and so there has been no noticeable increase in blood copper in any animals or humans used in trials.
In fact it has been found that introducing copper to the body in the form of supplements has the effect of countering many of the degenerative diseases of aging.
There is, however, a warning that has been put out there about the overuse of copper peptide:
While moderate use of copper peptides stimulates collagen synthesis and has antioxidant effect (by stimulating the antioxidant enzyme superoxide dismutase), excessive use can have an opposite effect by increasing the levels of free copper and/or by triggering excessive production of metalloproteinases. Free copper promotes free radical damage and collagen breakdown leading to accelerated skin aging. Metalloproteinases can digest collagen and elastin, weakening the skin and causing sag. These problems do not seem to occur among the majority of copper peptide users. However, there are anecdotal reports indicating that such side-effects might happen with overuse or, rarely, even normal use in sensitive individuals. Ideally, a sufficiently large study is needed to better quantify these risks.
Brand Names Containing Copper Peptides
Copper peptides can be found in products such as Prox-N and Tricomin.
The following quote is information taken from a webpage that no longer exists about Tricomin – “it is one of the few products to have actually stimulated growth in intensive partial FDA trials. In Phase II clinical studies, it had very positive results on some of the 36 men who applied the treatment topically twice a day for 24 weeks. It uses a technology known as the “Copper Peptide Technology” to do this.
Copper’s ability to influence hair growth was discovered when it was noted that the hair follicles around treated wounds were significantly larger than in non-treated areas. The effects of copper peptides can be seen in a couple of ways: the first is that it increases follicle cell production; the second is that it decreases the rate at which hair follicles die.
There are a number of eyebrow regrowth products and conditioning products that have quoted the inclusion of peptides of some type among their ingredients. In fact the majority of the products used to enhance eyebrow growth are actually skin improvement products with the side-effect being the improvement of eyebrow health.
Some of these products include LashFood Nano-Peptide Eyebrow Conditioner, RapidBrow Eyebrow Enhancing Serum, Measurable Difference Lash and Brow Amplifying Serum, MyChelle Ultimate Lash and Brow Serum, NYX Natural Grow Brow Serum and ModelSupplies Rapid Brow Grow Formula.